Wednesday, July 29, 2009

cute attack!

anna k the bernese mountain puppers

watch - Kids (1995)


Tuesday, July 28, 2009

eat more blue M&M's!

this is part cute attack! too, but primarily its a call to eat as much blue M&M's you can reduce cancer and induce vomiting!

(CNN) -- The same blue food dye found in M&Ms and Gatorade could be used to reduce damage caused by spine injuries, offering a better chance of recovery, according to new research.

Researchers at the University of Rochester Medical Center found that when they injected the compound Brilliant Blue G (BBG) into rats suffering spinal cord injuries, the rodents were able to walk again, albeit with a limp.

The only side effect was that the treated mice temporarily turned blue.

The results of the study, published in the "Proceedings of the National Academy of Sciences," build on research conducted by the same center five years ago.

In August 2004, scientists revealed how Adenosine triphosphate, which is known as ATP and described as the "energy currency of life," surges to the spinal cord soon after injury occurs.

Researchers found that the sudden influx of ATP killed off healthy cells, making the initial injury far worse. But when they injected oxidized ATP into the injury, it was found to block the effect of ATP, allowing the injured rats to recover and walk again.

"While we achieved great results when oxidized ATP was injected directly into the spinal cord, this method would not be practical for use with spinal cord-injured patients," said lead researcher Maiken Nedergaard, professor of Neurosurgery and director of the Center for Translational Neuromedicine at the University of Rochester Medical Center.

"First, no one wants to put a needle into a spinal cord that has just been severely injured, so we knew we needed to find another way to quickly deliver an agent that would stop ATP from killing healthy motor neurons. Second, the compound we initially used, oxidized ATP, cannot be injected into the bloodstream because of its dangerous side effects."

Back in 2004, Nedergaard's team discovered that the spinal cord was rich in a molecule called P2X7, which is also known as "the death receptor" for its ability to allow ATP to latch onto motor neurons and send the signals which eventually kill them.

Nedergaard knew that BBG could thwart the function of P2X7, and its similarity to a blue food dye approved by the Food and Drug Administration (FDA) in 1982 gave her the confidence to test it intravenously.

It worked. The rats given BBG immediately after their injury could walk again with a limp. Those that didn't receive a dose never regained their mobility.

Nedergaard told CNN that there is currently no standard treatment for patients with spinal injury when they reach the hospital emergency room.

"Right now we only treat 15 percent of the patients we receive with steroids and many hospitals question if that even works for that 15 percent; it's a very moderate benefit to only a subset of patients. So right now 85 percent of patients are untreated," she said.

Nedergaard said the research team isn't claiming that BBG can cure spinal injuries, instead that it offers a potential improvement in patients' condition.

"Even a moderate improvement in functional performance of the patient is a big, big event for these patients," she said. "They can control their bladder. If they can just take small steps instead of sitting in a wheelchair all the time, it's a tremendous benefit for these patients," she added.

The dose must be administered immediately after the injury, before additional tissue dies as a result of the initial injury.

Researchers are currently pulling together an application to be lodged with the FDA to stage the first clinical trials of BBG on human patients.

"Our hope is that this work will lead to a practical, safe agent that can be given to patients shortly after injury, for the purpose of decreasing the secondary damage that we have to otherwise expect," said Steven Goldman, Chair of the University of Rochester Department of Neurology.

read about it here

Monday, July 27, 2009

places i'd rather be

Thursday, July 23, 2009

Wu-Tang Lego: Da Mystery of Chessboxin'

Wu-Tang Lego: Da Mystery of Chessboxin' from davo on Vimeo.

fashion ridics

the shoes for ogres....ridiculous shape and im sure its not that comfy...$3700...super cheap!
Marloes ten Bhömer created these using a single piece of folded leather and stainless steel construction.

Wednesday, July 22, 2009

Steve Caballero

huuuuuuge! Steve Caballero. Sunset frontside wall ride on the monolith at Lake Cunningham skatepark. photo by Potwin 2009

his blog

Monday, July 20, 2009

Kid Cudi - I poke her face video

definitely different from the norm

Sunday, July 19, 2009

the truck

bigfoot. i always wanted to smash shit with bigfoot.

Friday, July 17, 2009

cute attack!

a circus lion taking a bath

a doggie smoking a pipe

Gorilla in Paris . FUCK YEAH!

ed wonka killing it with the Gorilla Family riding in the streets of Paris. Also features the "Dans ta gueule, puceau!" polo team and Suburbs Crew. The movie was directed by Renaud Skyronka.

Gorilla in Paris from Gorilla Bicycles on Vimeo.

Wednesday, July 15, 2009

Anima D'Acciaio Trailer Ver5.1

this is amazing to me. soul is not produced in mass produced frames. i agree.
A film by Daniel Leeb of Cinecycle Productions

A Portrait of the legendary Italian Frame Builder Giovanni Pelizzoli aka "Ciocc" . Ciocc shares his wisdom and life story while handbuilding a revolutionary new frame for urban fixed gear cycling. Ciocc demonstrates that the tradition and craft of framebuilding's Golden age can be re-born and push the technical frontier of Cycling's future. . also Feaures Ed "Wonka" La Forte and Antonio Colombo with an original soundtrack composed by Amedeo & Simone Pace of BlondeRedhead.

Anima D'Acciaio Trailer Ver5.1 from Cinecycle on Vimeo.

Monday, July 13, 2009

A Tribe Called Quest

1nce Again. classic.

Thursday, July 9, 2009

They Came From… Snowboard Trailer

Factor-Films upcoming film - They Came From… HD snowboarding goodness.

Factor Films presents THEY CAME FROM... Vimeo

Wednesday, July 8, 2009

Yvon Le Caer

crossed the English channel by pedaling across it. of course there were some pontoons involved. 16hrs 42min. record.

about yvon

Porsche: Legend from Stephen Fitzgerald


Porsche: Legend from Stephen Fitzgerald on Vimeo.

Monday, July 6, 2009

Bruce Springsteen

Brucey B kid capri from nate dizzle on Vimeo.

im too lazy to post shit. im recovering from the july 4th weekend. here's a music video i like and song.

Saturday, July 4, 2009

Black Ivory - I keep asking you questions

Wednesday, July 1, 2009

the godzilla of jellyfish invade japan!

holy crap. its not godzilla but worse, JELLYFISH! BIG ASS ONES!

"Japanese researchers monitoring the activity of giant jellyfish in Chinese waters are warning of a potentially historic and catastrophic invasion this year.
Marine surveys conducted in late June have revealed alarming numbers of Nomura’s jellyfish — massive creatures that grow up to 2 meters (6 ft 7 in) in diameter and weigh as much as to 220 kilograms (about 450 lbs) — lurking in the Yellow Sea and East China Sea. The researchers warn that ocean currents may bring swarms of the monster jellies to Japan, which has been plagued by similar invasions in recent years.

Based on what they have seen so far, the researchers warn this year’s onslaught of Nomura’s jellyfish (Nemopilema nomurai, or Echizen kurage in Japanese) could deliver a massive blow to Japan’s fishing industry, rivaling even the devastating 2005 deluge that caused tens of billions of yen (hundreds of millions of dollars) in damage nationwide.
The surveys are being conducted by a team led by Shinichi Ue, a professor of biological oceanography at Hiroshima University who also chairs a government research committee tasked with developing technology to predict and control jellyfish explosions. Ue has been monitoring the population density of Nomura’s jellyfish in the southern Yellow Sea and northern East China Sea since 2006.
Between June 20 and 24, 2009, Ue’s team observed numerous specimens with umbrellas measuring 10 to 50 centimeters across, and they calculated an average distribution of 2.14 jellyfish per 100 square meters. This figure is more than 200 times higher than the 0.01 jellyfish per 100 square meters observed in the same region in 2008. It is also nearly triple the 0.77 jellyfish per 100 square meters observed in 2007, when the fishing industry in the Sea of Japan suffered widespread damage."


bar rafaeli nekkid!

maaaan...shes sooo busted! soo very kidding.

the worlds first stealth fighter

that luftwaffe and Hermann Göring were a tricky bunch. who knows what would have happened if this bad mother-effer made to production.

"As it turns out, Hitler had an stealth fighter in the Ho 2-29. Thanks to the use of wood and carbon—which increased its radar absortion—jet engines integrated into the fuselage, and its blended surfaces, the plane could have been in London eight minutes after the British radar system detected it. In comparison, other planes took 19 minutes since detection to target, which gave the RAF fighter enough time to scramble and hunt down the bastards. The Ho 2-29 would have made the interception almost impossible, if at all."

the Horten 2-29 was reproduced by northrop grumman and tested to see if it would evade wwII era radars. currently residing at Air and Space Museum’s Paul E. Garber Restoration and Storage Facility.


mother effing grossness

massive worm found in a north carolina sewer, it looks like throbbing clit if you ask me!

zooey lets go-e!

(500) Days of Summer is coming out this season.

the soundtrack is pretty good too